If you interested for using firefox addon, I think twitbin is one of twitter tool that you can choose. Why? Twitbin is a firefox extension that allows you to keep up with all of your Twitter conversations right from your browser sidebar. Send messages, receive messages, share links, and more from Twitbin, the best twitter addon for firefox out there.Twitbin provides all the same funtionality that Twitter does. You can view pulic or private tweets, as well as direct messages, replies, and if you have favorited any tweets, you can see those too. You get to chose the refresh time from 2 minutes to 15 minutes. Twitbin brings the greatness of Twitter to your Firefox browser.
System requirements when you want to use twitbin are Firefox 2.0 or higher, 1MB Hard drive space, 10MB of RAM memory, Windows, Mac, or Linux